'INDISCRIMINATE LITIGATION'
Last month, Missouri became the first U.S. state to sue the Chinese government over its handling of the coronavirus, saying China's response to the outbreak that originated in the city of Wuhan brought devastating economic losses to the state.
Wang said such lawsuits lacked any legal basis.
"The China of today is not the China of a century ago, and nor is the world," he added.
"If you want to infringe upon China's sovereignty and dignity with indiscriminate litigation, and extort the fruits of the hard work of the Chinese people, I am afraid this is a daydream and you'll only humiliate yourself."
Wang also offered his strong support for the World Health Organization (WHO) and its chief, Tedros Adhanom Ghebreyesus, frequent targets of U.S criticism.
"To support the WHO is to support saving lives. This is the choice any country with a conscience should make," he said.
Trump, who has accused the agency of being "China centric", has threatened to permanently halt funding to the WHO and to reconsider his country's membership of the agency.
