The first-leg matches of UEFA Europa League's Round of 16 will kick off on Thursday.
Among the ties, Rennes and Arsenal; Valencia and Krasnodar; Frankfurt and Inter; Napoli and Salzburg have never met in an UEFA competition before.
Seven sides among 16 teams are either former UEFA Cup or UEFA Europa League winners; Chelsea (2013), Frankfurt (1980), Internazionale (1991, 1994, 1998), Napoli (1989), Sevilla (2006, 2007, 2014, 2015, 2016), Valencia (2004) and Zenit (2008).
The second-leg matches will be played on March 14.
The first-leg matches are as follow:
1755GMT
Dinamo Zagreb vs. Benfica
Frankfurt vs. Internazionale
Rennes vs. Arsenal
Sevilla vs. Slavia Praha
Zenit vs. Villarreal
2000GMT
Chelsea vs. Dynamo Kyiv
Napoli vs. Salzburg
Valencia vs. Krasnodar
