Israeli protesters breached police barriers set up on the road leading to Prime Minister Benjamin Netanyahu's residence in West Jerusalem on Tuesday.
Thousands also demonstrated outside the Knesset, or Israeli parliament, for a third straight day, demanding early elections and a prisoner exchange deal with the Palestinian group Hamas.
Israel's public broadcaster Kan aired a video showing dozens of protesters removing police barriers and clashing with officers near Netanyahu's house.
The police said in a statement that they removed protesters who attempted to approach the residence.
They added that some rioters hurled flares at police officers.
Hamas, which is believed to be holding nearly 130 Israeli hostages, demands an end to Israel's offensive on the Gaza Strip in return for a hostage deal with Tel Aviv.
A previous deal in November last year saw the release of 81 Israelis and 24 foreigners in exchange for 240 Palestinians, including 71 women and 169 children.
Israel has waged a deadly military offensive on the Gaza Strip since an Oct. 7 cross-border attack by Hamas which killed some 1,200 people.
More than 32,900 Palestinians have since been killed and 75,494 others injured amid mass destruction and shortages of necessities.
Israel has also imposed a crippling blockade on the Gaza Strip, leaving its population, particularly residents of northern Gaza, on the verge of starvation.
The Israeli war has pushed 85% of Gaza's population into internal displacement amid acute shortages of food, clean water and medicine, while 60% of the enclave's infrastructure has been damaged or destroyed, according to the UN.
Israel stands accused of genocide at the International Court of Justice (ICJ), which on Thursday asked it to do more to prevent famine in Gaza.
